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Tetanus vaccine, also known as tetanus toxoid (TT), is a toxoid vaccine used to prevent tetanus. [2] During childhood, five doses are recommended, with a sixth given during adolescence. [2] After three doses, almost everyone is initially immune, [2] but additional doses every ten years are recommended to maintain immunity. [3]
Tetanus immunoglobulin (TIG), [1] also called tetanus antibodies or tetanus antitoxin. [46] It can be given as intravenous therapy or by intramuscular injection. Antibiotic therapy to reduce toxin production. Metronidazole intravenous (IV) is a preferred treatment. [48] Benzodiazepines can be used to control muscle spasms.
Tdap (also TDP) is a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine. It was licensed in the United States for use in adults and adolescents on 10 June 2005. [ 26 ] Two Tdap vaccines are available in the US.
The 2006 edition of The Green book has 468 pages, divided generally into two parts, preceded by a contents page, acknowledgements and preface, and followed by two indexes, one of vaccines by proprietary name and the other of vaccines by common name.
The tetanus disease requires a booster dose every 10 years, or in some circumstances immediately following infection of tetanus. Td is the name of the booster for adults, and differs from the primary dose in that it does not include immunization against pertussis (whooping cough). [ 11 ]
Anti-tetanus immunoglobulin, also known as tetanus immune globulin (TIG) and tetanus antitoxin, is a medication made up of antibodies against the tetanus toxin. [1] It is used to prevent tetanus in those who have a wound that is at high risk, have not been fully vaccinated with tetanus toxoid , or have HIV/AIDS .
Tetanus is often referred to as lockjaw due to the fact that the bacteria (Clostridium tetani) cause the muscles of the jaw to tighten, which makes the infected person unable to open their mouth. Today in the United States, tetanus is an uncommon disease with an average of only 29 cases reported per year between 1996 and 2009.
In such cases, it can be given with or without tetanus immunoglobulin (also called tetanus antibodies or tetanus antitoxin [13]). It can be given as intravenous therapy or by intramuscular injection. [citation needed] The guidelines for such events in the United States for non-pregnant people 11 years and older are as follows: [14]