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  2. Germ plasm - Wikipedia

    en.wikipedia.org/wiki/Germ_plasm

    Other cells of the body do not function as agents of heredity. The effect is one-way: germ cells produce somatic cells, and more germ cells; the germ cells are not affected by anything the somatic cells learn or any ability the body acquires during its life. Genetic information cannot pass from soma to germ plasm and on to the next generation.

  3. Germline mosaicism - Wikipedia

    en.wikipedia.org/wiki/Germline_Mosaicism

    Somatic cells are more commonly used for genetic analysis because they are easier to obtain than gametes. If the disease is a result of pure germline mosaicism, then the disease causing mutant allele would never be present in the somatic cells. This is a source of uncertainty for genetic counselling. An individual may still be a carrier for a ...

  4. Somatic cell - Wikipedia

    en.wikipedia.org/wiki/Somatic_cell

    In mammals, somatic cells make up all the internal organs, skin, bones, blood and connective tissue, while mammalian germ cells give rise to spermatozoa and ova which fuse during fertilization to produce a cell called a zygote, which divides and differentiates into the cells of an embryo. There are approximately 220 types of somatic cell in the ...

  5. Mosaic (genetics) - Wikipedia

    en.wikipedia.org/wiki/Mosaic_(genetics)

    Gonosomal mosaicism is a type of somatic mosaicism that occurs very early in the organisms development and thus is present within both germline and somatic cells. [1] [22] Somatic mosaicism is not generally inheritable as it does not usually affect germ cells. In the instance of gonosomal mosaicism, organisms have the potential to pass the ...

  6. Somatic mutation - Wikipedia

    en.wikipedia.org/wiki/Somatic_mutation

    For example, in mammals, somatic cells make up the internal organs, skin, bones, blood, and connective tissue. [1] In most animals, separation of germ cells from somatic cells (germline development) occurs during early stages of development. Once this segregation has occurred in the embryo, any mutation outside of the germline cells can not be ...

  7. Weismann barrier - Wikipedia

    en.wikipedia.org/wiki/Weismann_barrier

    Whatever may happen to those cells does not affect the next generation. The Weismann barrier, proposed by August Weismann, is the strict distinction between the "immortal" germ cell lineages producing gametes and "disposable" somatic cells in animals (but not plants), in contrast to Charles Darwin's proposed pangenesis mechanism for inheritance.

  8. Soil-borne wheat mosaic virus - Wikipedia

    en.wikipedia.org/wiki/Soil-borne_wheat_mosaic_virus

    Soil-borne wheat mosaic virus is a rod-shaped plant pathogen that can cause severe stunting and mosaic in susceptible wheat, barley and rye cultivars. [1] The disease has often been misdiagnosed as a nutritional problem, but this has actually allowed in part for the fortuitous visual selection by breeding programs of resistant genotypes.

  9. Somatic hypermutation - Wikipedia

    en.wikipedia.org/wiki/Somatic_hypermutation

    Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g. microbes).A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements and allows the immune system to adapt its response to new threats during the lifetime of an organism. [1]