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  2. Anaphase - Wikipedia

    en.wikipedia.org/wiki/Anaphase

    A cell during anaphase. Microtubules are visible in green. Stages of late M phase in a vertebrate cell. Anaphase (from Ancient Greek ἀνα-() 'back, backward' and φάσις (phásis) 'appearance') is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell.

  3. Cell cycle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle_checkpoint

    There are many checkpoints in the cell cycle, [1] but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint. [2]

  4. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    Anaphase is a very short stage of the cell cycle and it occurs after the chromosomes align at the mitotic plate. Kinetochores emit anaphase-inhibition signals until their attachment to the mitotic spindle. Once the final chromosome is properly aligned and attached the final signal dissipates and triggers the abrupt shift to anaphase. [26]

  5. Cell cycle - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle

    It is a relatively short period of the cell cycle. M phase is complex and highly regulated. The sequence of events is divided into phases, corresponding to the completion of one set of activities and the start of the next. These phases are sequentially known as: prophase; prometaphase; metaphase; anaphase; telophase; A diagram of the mitotic phases

  6. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    After checkpoint deactivation and during the normal anaphase of the cell cycle, the anaphase promoting complex is activated through decreasing MCC activity. When this happens the enzyme complex polyubiquitinates the anaphase inhibitor securin. The ubiquitination and destruction of securin at the end of metaphase releases the active protease ...

  7. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    In late anaphase, chromosomes also reach their overall maximal condensation level, to help chromosome segregation and the re-formation of the nucleus. [54] In most animal cells, anaphase A precedes anaphase B, but some vertebrate egg cells demonstrate the opposite order of events. [52]

  8. Neuronal cell cycle - Wikipedia

    en.wikipedia.org/wiki/Neuronal_cell_cycle

    S phase is then driven by the binding of cyclin A with Cdk2. In late S phase, cyclin A binds with Cdk1 to promote late replication origins and also initiates the condensation of the chromatin in the late G2 phase. The G2/M phase transition is regulated by the formation of the Cdk1/cyclin B complex.

  9. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Following recombination, chromosome segregation occurs as indicated by the stages metaphase I and anaphase I in the meiosis diagram. Different pairs of chromosomes segregate independently of each other, a process termed “independent assortment of non-homologous chromosomes”. This process results in each gamete usually containing a mixture ...