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  2. AstraZeneca's Farxiga cuts death risk in heart failure ... - AOL

    www.aol.com/news/astrazenecas-farxiga-cuts-death...

    AstraZeneca's blockbuster diabetes drug Farxiga led to significant reductions in the risk of hospitalisation and death in people with all types of heart failure, according to study data released ...

  3. AstraZeneca diabetes drug gets U.S. nod to treat heart failure

    www.aol.com/news/astrazenecas-diabetes-drug-gets...

    The U.S. Food and Drug Administration (FDA) has approved Farxiga to reduce the risk of cardiovascular death and hospitalisation for heart failure in certain patients, regardless of their diabetes ...

  4. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment

  5. Cardiotonic agent - Wikipedia

    en.wikipedia.org/wiki/Cardiotonic_agent

    By reducing strain on the heart, this mechanism helps minimise the oxygen demand. Furthermore, calcium sensitizers provide an additional benefit. They open potassium channels in the heart muscle cells, resulting in vasodilation and improved blood flow. [53] This action reduces the workload on the heart.

  6. Arteriovenous oxygen difference - Wikipedia

    en.wikipedia.org/wiki/Arteriovenous_oxygen...

    The arteriovenous oxygen difference is usually taken by comparing the difference in the oxygen concentration of oxygenated blood in the femoral, brachial, or radial artery and the oxygen concentration in the deoxygenated blood from the mixed supply found in the pulmonary artery (as an indicator of the typical mixed venous supply).

  7. Vasodilation - Wikipedia

    en.wikipedia.org/wiki/Vasodilation

    The primary function of vasodilation is to increase blood flow in the body to tissues that need it most. This is often in response to a localized need for oxygen but can occur when the tissue in question is not receiving enough glucose, lipids, or other nutrients. Vasodilation, both localized and systemic, also facilitates immune response. [7]

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