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This movie depicts the 3-D structures of each of the representative conformations of the Markov State Model of Pin1 WW domain. In computational chemistry, conformational ensembles, also known as structural ensembles, are experimentally constrained computational models describing the structure of intrinsically unstructured proteins.
Structural holes is a concept from social network research, originally developed by Ronald Stuart Burt. A structural hole is understood as a gap between two individuals who have complementary sources to information. The study of structural holes spans the fields of sociology, economics, and computer science.
In the context to structural analysis, a structure refers to a body or system of connected parts used to support a load. Important examples related to Civil Engineering include buildings, bridges, and towers; and in other branches of engineering, ship and aircraft frames, tanks, pressure vessels, mechanical systems, and electrical supporting structures are important.
Constraint may refer to: Constraint (computer-aided design) , a demarcation of geometrical characteristics between two or more entities or solid modeling bodies Constraint (mathematics) , a condition of an optimization problem that the solution must satisfy
With the definition of the design space, regions or components in the model that cannot be modified during the course of the optimization are considered as non-design regions. constraints ((),) a characteristic that the solution must satisfy. Examples are the maximum amount of material to be distributed (volume constraint) or maximum stress values.
Facts are constraints that are assumed to always hold; Predicates are parameterized constraints, and can be used to represent operations; Functions are expressions that return results; Assertions are assumptions about the model; Because Alloy is a declarative language the meaning of a model is unaffected by the order of statements.
Numerically, this can be achieved by using matrix structural analyses, finite element method (FEM) or the moment distribution method (Hardy Cross) . Practically, a structure is called 'statically overdetermined' when it comprises more mechanical constraints – like walls, columns or bolts – than absolutely necessary for stability.
The theory of constraints (TOC) is a management paradigm that views any manageable system as being limited in achieving more of its goals by a very small number of constraints. There is always at least one constraint, and TOC uses a focusing process to identify the constraint and restructure the rest of the organization around it.