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Some factors that indicate a poor prognosis are a QRS greater than 120 milliseconds, a delay in diagnosis, high NYHA class, multiparity, African descent. [ 7 ] Mortality estimates have significant differences depending on the racial group being studied, the geographical location, and the length of follow-up in the study.
These findings are the result of a 2018 literature review. [68] This followed a 2015 meta analysis that showed that PCT had a sensitivity of 90% and a specificity of 98% in judging viral versus bacterial meningitis. PCT also outperformed other biomarkers such as C-reactive protein. [69]
Serum amyloid A (SAA) is also an acute phase marker that responds rapidly. Similar to CRP, levels of acute-phase SAA increase within hours after inflammatory stimulus, and the magnitude of increase may be greater than that of CRP. Relatively trivial inflammatory stimuli can lead to SAA responses.
C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells .
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Scholarpedia is an English-language wiki-based online encyclopedia with features commonly associated with open-access online academic journals, which aims to have quality content in science and medicine. Scholarpedia articles are written by invited or approved expert authors and are subject to peer review. [3]
The "passivity" agreement FDIC wants BlackRock to sign is designed to assure bank regulators that the giant money manager will remain a "passive" owner of an FDIC-supervised bank and won’t exert ...
This table contains supercentenarian claims with either a known death date or no confirmation for more than two years that they were still alive. Only claims greater than that of Jeanne Calment, who died at the age of 122 years, 164 days, but under 130 years are included. They are listed in order of age as of the date of death or date last ...