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Elmer Verner McCollum (March 3, 1879 – November 15, 1967) was an American biochemist known for his work on the influence of diet on health. [2] [3] McCollum is also remembered for starting the first rat colony in the United States to be used for nutrition research.
Macronutrients are defined as a class of chemical compounds which humans consume in relatively large quantities compared to vitamins and minerals which provide humans with energy. Fat has a food energy content of 38 kilojoules per gram (9 kilocalories per gram) proteins and carbohydrates 17 kJ/g (4 kcal/g).
Macronutrients, especially protein, fat and carbohydrates, have been the focus components of the study of (human) nutrition since the 19th century. Until the discovery of vitamins and vital substances, the quality of nutrition was measured exclusively by the intake of nutritional energy .
The macronutrients are taken-up in larger quantities; hydrogen, oxygen, nitrogen and carbon contribute to over 95% of a plant's entire biomass on a dry matter weight basis. Micronutrients are present in plant tissue in quantities measured in parts per million, ranging from 0.1 [ 3 ] to 200 ppm, or less than 0.02% dry weight.
All the vitamins were discovered between 1913 and 1948. Historically, when intake of vitamins from diet was lacking, the results were vitamin deficiency diseases. Then, starting in 1935, commercially produced tablets of yeast-extract vitamin B complex and semi-synthetic vitamin C became available. [ 8 ]
As an example of its accuracy, 18th century scientist Guillaume Le Gentil, during a visit to Pondicherry, India, found the Indian computations (based on Aryabhata's computational paradigm) of the duration of the lunar eclipse of 30 August 1765 to be short by 41 seconds, whereas his charts (by Tobias Mayer, 1752) were long by 68 seconds. [89]
The Bellwether: Why Ohio Picks the President (Ohio University Press, 2016) Lamis, Alexander, and Brian Usher. Ohio Politics (2007) 544pp. Maizlish, Stephen E. The Triumph of Sectionalism: The Transformation of Ohio Politics, 1844–1856 (1983) Miller, Richard F. States at War, Volume 5: A Reference Guide for Ohio in the Civil War (2015).
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...