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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [70] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [22] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
In Phase III trials, the most common adverse effects were dizziness, drowsiness and disorientation; 12% of subjects stopped taking the drug because of the side effects. [57] Dronabinol (brand names Marinol and Syndros) is a delta-9-THC containing drug for treating HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting. [58]
Another problem, despite the dosage written on a brand’s packaging, is that the actual amount of THC varies from product to product. This makes it even harder to pin down how much is too much.
Short-term use increases the risk of minor and major adverse effects. [7] Common side effects include dizziness, feeling tired, vomiting, and hallucinations. [7] Long-term effects of cannabis are not clear. [7] Concerns include memory and cognition problems, risk of addiction, schizophrenia in young people, and the risk of children taking it by ...
Cannabis material can be leached in high-proof spirits (often grain alcohol) to create a "Green Dragon". Cannabis can also be consumed as a cannabis tea and many other beverages. Although THC is lipophilic and only slightly water soluble (with a solubility of 2.8 mg per liter), [13] enough THC can be dissolved to make a mildly psychoactive tea ...
In the US, men are over twice as likely to use marijuana as women, and 18–29-year-olds are six times more likely to use as over-65-year-olds. [47] In 2015, a record 44% of the US population has tried marijuana in their lifetime, an increase from 38% in 2013 and 33% in 1985. [47]