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Shellfish allergies are highly cross reactive, but its prevalence is much higher than that of fish allergy. Shellfish allergy is the leading cause of food allergy in U.S adults. [31] As of 2018 six allergens have been identified to prawn alone; along with crab, it is the major culprit of seafood anaphylaxis. [13]
Cross-contamination of food occurs when allergens are unintentionally transferred from one food item to another, often through shared cooking equipment, not properly cleaned surfaces, or utensils. This can lead to severe allergic reactions in individuals with food allergies, even if the allergen is present in trace amounts. [ 51 ]
An allergen is an otherwise harmless substance that triggers an allergic reaction in sensitive individuals by stimulating an immune response.. In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. [1]
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Even minute amounts, such as coloring or spices, must be listed if they contain any proteins from these major allergens. [8] Manufacturers are given two ways in which to label food allergens. They may either state the food source name of a major food allergen in the list of ingredients, most often contained within parenthesis.
The terms CCD or CCDs describe protein-linked carbohydrate structures responsible for the phenomenon of cross-reactivity of sera from allergic patients towards a wide range of allergens from plants and insects. In serum-based allergy diagnosis, antibodies of the IgE class directed against CCDs therefore give the impression of polysensitization ...
Precautionary statements are one of the key elements for the labelling of containers under the GHS, along with: [4] an identification of the product; one or more hazard pictograms (where necessary) a signal word – either Danger or Warning – where necessary; hazard statements, indicating the nature and degree of the risks posed by the product
Warning Letters should only be issued for violations of regulatory significance, i.e., those that may actually lead to an enforcement action if the documented violations are not promptly and adequately corrected. A Warning Letter is one of the Agency's principal means of achieving prompt voluntary compliance with the Act. [1]