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A phase-gate process (also referred to as a waterfall process) is a project management technique in which an initiative or project (e.g., new product development, software development, process improvement, business change) is divided into distinct stages or phases, separated by decision points (known as gates).
The switches maintain the orderly progression of the cell cycle and act as checkpoints to ensure that each phase has been properly completed before progression to the next phase. [1] For example, Cdk, or cyclin dependent kinase , is a major control switch for the cell cycle and it allows the cell to move from G1 to S or G2 to M by adding ...
Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Homeostasis: regulation of the internal environment to maintain a constant state; for example, sweating to reduce temperature
The phase diagrams are shown in Figure 5. Tracking the x-intercepts in the phase diagram as r changes, there are two fixed point trajectories which intersect at the origin; this is the bifurcation point (intuitively, when the number of x-intercepts in the phase portrait changes). The left fixed point is always unstable, and the right one stable.
Ions often move through the segments of the channel pore in a single file nearly as quickly as the ions move through the free solution. In many ion channels, passage through the pore is governed by a "gate", which may be opened or closed in response to chemical or electrical signals, temperature, or mechanical force. [citation needed]
The exact mechanism by which this movement occurs is not currently agreed upon, however the canonical, transporter, paddle, and twisted models are examples of current theories. [7] Movement of the voltage-sensor triggers a conformational change of the gate of the conducting pathway, controlling the flow of ions through the channel. [3]
Cell synchronization is a process by which cells in a culture at different stages of the cell cycle are brought to the same phase. Cell synchrony is a vital process in the study of cells progressing through the cell cycle as it allows population-wide data to be collected rather than relying solely on single-cell experiments.
The G1 phase cyclin-dependent kinase works together with S phase cyclin-dependent kinase targeting p27 for degradation. In turn, this allows for full activation of Cyclin A:Cdk2, a complex which phosphorylates E2F 1-3 initiating their disassociation from the DNA promoter sites. This allows E2F 6–8 to bind to the DNA and inhibit transcription ...