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Iobitridol is nonionic but water-soluble, [1] having some OH groups in its side chains designed to mask the central hydrophobic benzene ring. [ 5 ] The solution has a low osmolarity of 695 ( Xenetix 300 ) or 915 mOsm /kg H 2 O ( Xenetix 350 ), which means it causes fewer allergic and allergy-like reactions, as well as less extravasation ...
Iontophoresis is useful in laboratory experiments, especially in neuropharmacology. [5] Transmitter molecules naturally pass signals between neurons.By microelectrophoretic techniques, including microiontophoresis, neurotransmitters and other chemical agents can be artificially administered very near living and naturally functioning neurons, the activity of which can be simultaneously recorded.
Ferric subsulfate (also known as Monsel's solution) is often used by Jewish burial societies (chevra kadisha) to stop post-mortem bleeding.Since Jewish burial does not allow any external skin adhesives such as bandages, tape, glue or resin, ferric subsulfate is an effective way to stop post-mortem bleeding.
Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.
[1] Formulation studies then consider such factors as particle size, polymorphism, pH, and solubility, as all of these can influence bioavailability and hence the activity of a drug. The drug must be combined with inactive ingredients by a method that ensures that the quantity of drug present is consistent in each dosage unit e.g. each tablet ...
3. Agarawal A., et al. Follow-up experience using histidine-tryptophan-ketoglutarate solution in clinical pancreas transplantation Transplant Proc. 2005;37:3523–3526. 4. Pokorny H., et al.: Histidine-tryptophan-ketoglutarate solution for organ preservation in human liver transplantation — a prospective multi-centre observation study.
In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer.The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy ...
In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.