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  2. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    Since the first description of multiple sclerosis (MS) by Charcot, the Neurological community has been striving to create reliable and reproducible criteria for diagnosis of MS. [32] The first attempts were made by Charcot himself, followed by Marburg and later Allison. The first criteria however were lacking in sensitivity and specificity for ...

  3. McDonald criteria - Wikipedia

    en.wikipedia.org/wiki/McDonald_criteria

    The McDonald criteria maintained a scheme for diagnosing MS based solely on clinical grounds but also proposed for the first time that when clinical evidence is lacking, magnetic resonance imaging (MRI) findings can serve as surrogates for dissemination in space (DIS) and/or time (DIT) to diagnose MS. [5] The criteria try to prove the existence ...

  4. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Main symptoms of multiple sclerosis Symptoms and findings in multiple sclerosis. Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing (), visual ...

  5. Montel Williams opens up about his first symptoms of multiple ...

    www.aol.com/lifestyle/montel-williams-opens...

    Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...

  6. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

  7. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    Multiple sclerosis is considered a disease of the white matter because normally lesions appear in this area, but it is also possible to find some of them in the grey matter. [ 30 ] Using high field MRI system, with several variants several areas show lesions, and can be spacially classified in infratentorial, callosal, juxtacortical ...

  8. Christina Applegate Details Extent of Brain Damage Caused By MS

    www.aol.com/christina-applegate-details-extent...

    Christina Applegate. Christina Applegate shed new light on her battle with multiple sclerosis (MS).. When it comes to updates, the 52-year-old actress has been on a roll lately, frankly speaking ...

  9. Biomarkers of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_multiple...

    Anti-MOG seropositive patients do not respond to approved MS medications. [16] In fact, it seems that MS patients with anti-MOG positivity could be considered a different disease in the near future. Comparative Effectiveness Research (CER) is an emerging field in Multiple Sclerosis treatment.

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