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There is no standard medical or surgical treatment for acrocyanosis, and treatment, other than reassurance and avoidance of cold, is usually unnecessary. The patient is reassured that no serious illness is present. A sympathectomy would alleviate the cyanosis by disrupting the fibers of the sympathetic nervous system to the area. [3]
Cold agglutinin-mediated acrocyanosis differs from Raynaud phenomenon. In Raynaud phenomena, caused by vasospasm, a triphasic color change occurs, from white to blue to red, based on vasculature response. No evidence of such a response exists in cold agglutinin disease. Other symptoms
Symptoms of AIHA may be due to the underlying anemia; including shortness of breath or dyspnea, fatigue, headache, muscle weakness and pallor. [10] In cold agglutinin disease (cold antibody type), agglutination and impaired passage of red blood cells through capillaries in the extremities causes acrocyanosis and Raynaud phenomenon with a rare complication of gangrene [4]
Cure4Kids for Kids is a community outreach program intended to help children, their parents, and teachers understand the basic science of cancer and its treatment. With culturally sensitive and age-appropriate content, the program is designed to educate children, parents and teachers about cancer and dispel common misconceptions about childhood ...
Cold agglutinin disease (CAD) is a rare autoimmune disease characterized by the presence of high concentrations of circulating cold sensitive antibodies, usually IgM and autoantibodies that are also active at temperatures below 30 °C (86 °F), [1] directed against red blood cells, causing them to agglutinate and undergo lysis. [2]
CURE International, based in Grand Rapids, MI, is a Christian nonprofit organization that owns and operates eight charitable children's hospitals around the world. [1] CURE provides medical care to pediatric patients with orthopedic , reconstructive plastic , and neurological conditions.
The body's network of blood vessels is also affected. Children with this disorder may experience rashes of tiny red spots caused by bleeding under the skin and blue discoloration in the hands and feet due to reduced oxygen in the blood (acrocyanosis). Chronic diarrhea is another common feature of ethylmalonic encephalopathy. [3]
There are documented cases using both conservative and invasive treatments, including skin grafting and/or the application of nonadhesive dressing alongside topical corticosteroids to reduce inflammation. However, the use of steroids may exacerbate fungal infections if the aerosol product used is an antifungal medicine.