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  2. List of adverse effects of valproate - Wikipedia

    en.wikipedia.org/wiki/List_of_adverse_effects_of...

    Liver failure; Pancreatitis (these two usually occur in first 6 months and can be fatal); Leukopenia (low white blood cell count); Neutropenia (low neutrophil count); Pure red cell aplasia

  3. List of adverse effects of valproate semisodium - Wikipedia

    en.wikipedia.org/wiki/List_of_adverse_effects_of...

    Reversible dementia; Reversible cerebral atrophy; Abnormal behaviour [b]; Psychomotor hyperactivity [b]; Learning disorder [b]; Hyperammonaemia; Hypothyroidism; Bone marrow failure

  4. Valproate - Wikipedia

    en.wikipedia.org/wiki/Valproate

    They can be given intravenously or by mouth, and the tablet forms exist in both long- and short-acting formulations. [7] Common side effects of valproate include nausea, vomiting, somnolence, and dry mouth. [7] Serious side effects can include liver failure, and regular monitoring of liver function tests is therefore recommended. [7]

  5. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds ...

  6. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]

  7. Pethidine - Wikipedia

    en.wikipedia.org/wiki/Pethidine

    Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous, or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975, 60% of doctors prescribed it for acute pain and 22% for ...

  8. Estradiol cypionate - Wikipedia

    en.wikipedia.org/wiki/Estradiol_cypionate

    Examples of such side effects include breast tenderness and enlargement, nausea, vomiting, bloating, edema, headache, migraine, and melasma. [ 54 ] [ 55 ] High-dose estrogen therapy with estradiol cypionate injections may also cause an increased risk of thromboembolism , changes in blood lipid profile , increased insulin resistance , and ...

  9. Medroxyprogesterone acetate - Wikipedia

    en.wikipedia.org/wiki/Medroxyprogesterone_acetate

    In addition to single-drug formulations, MPA is available in the form of oral tablets in combination with conjugated estrogens (CEEs), estradiol, and estradiol valerate for use in menopausal hormone therapy, and is available in combination with estradiol cypionate in a microcrystalline aqueous suspension as a combined injectable contraceptive.