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Immunohistochemistry for CK7 of a metastatic undifferentiated carcinoma to a lymph node. Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas (staining positive) from colonic and prostate cancers (negative), respectively.
Expression of these cytokeratins is largely organ or tissue specific. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus a specific cytokeratin expression profile allows the identification of epithelial ...
2625 14462 Ensembl ENSG00000107485 ENSMUSG00000015619 UniProt P23771 P23772 RefSeq (mRNA) NM_001002295 NM_002051 NM_008091 NM_001355110 NM_001355111 NM_001355112 RefSeq (protein) NP_001002295 NP_002042 NP_032117 NP_001342039 NP_001342040 NP_001342041 Location (UCSC) Chr 10: 8.05 – 8.08 Mb Chr 2: 9.86 – 9.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse GATA3 is a transcription ...
Epigenetics of human development is the study of how epigenetics (hertiable characteristics that do not involve changes in DNA sequence) effects human development. Development before birth, including gametogenesis , embryogenesis , and fetal development , is the process of body development from the gametes are formed to eventually combine into ...
Strength of natural selection plot as a function of age. The antagonistic pleiotropy hypothesis (APT) is a theory in evolutionary biology that suggests certain genes may confer beneficial effects early in an organism's life, enhancing reproductive success, while also causing detrimental effects later in life, contributing to the aging process.
Research in Human Development is a quarterly peer-reviewed interdisciplinary scientific journal that publishes research on all aspects of human development. Its scope includes the perspectives of biology, psychology, and sociology, among other disciplines. It was established in 2004 and is published by Taylor & Francis.
Human Development is a quarterly peer-reviewed scientific journal covering all aspects of human development, particularly developmental psychology. Its scope includes disparate disciplines such as anthropology, biology, education, psychology, and sociology, among others. [1] The journal is published by Karger Publishers (Basel).
From position and maternal effects on gene expression to epigenetic inheritance [6] to the active construction and intergenerational transmission of enduring niches, [3] development systems theory argues that not only inheritance but evolution as a whole can be understood only by taking into account a far wider range of ‘reproducers’ or ...