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  2. Monoamine oxidase - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase

    Monoamine oxidase A and B share roughly 70% of their structure and both have substrate binding sites that are predominantly hydrophobic. Two tyrosine residues (398, 435 within MAO-B , 407 and 444 within MAO-A ) in the binding pocket that are commonly involved in inhibitor activity have been hypothesized to be relevant to orienting substrates ...

  3. Monoamine oxidase A - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase_A

    Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. [ 5 ] [ 6 ] This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines , such as norepinephrine , serotonin and tyramine .

  4. Monoamine oxidase B - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase_B

    Monoamine oxidase B (MAO-B) is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is an enzyme located in the outer mitochondrial membrane .

  5. Monoamine neurotransmitter - Wikipedia

    en.wikipedia.org/wiki/Monoamine_neurotransmitter

    After release into the synaptic cleft, monoamine neurotransmitter action is ended by reuptake into the presynaptic terminal. There, they can be repackaged into synaptic vesicles or degraded by the enzyme monoamine oxidase (MAO), which is a target of monoamine oxidase inhibitors, a class of antidepressants. [citation needed]

  6. Monoamine oxidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor

    Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants , especially for treatment-resistant depression and atypical depression . [ 1 ]

  7. Flavin-containing amine oxidoreductase - Wikipedia

    en.wikipedia.org/wiki/Flavin-containing_amine...

    Flavin-containing amine oxidoreductases are a family of various amine oxidases, including maize polyamine oxidase (PAO), [2] L-amino acid oxidases (LAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes.

  8. 15 over-the-top examples of wealth and luxury I saw on my ...

    www.aol.com/15-over-top-examples-wealth...

    Meanwhile, a trip to Aspen, Colorado, transformed my definition of luxury. In Paris and New York, five-star hotels and Michelin-star restaurants coexist alongside $1 pizza and cheap crepe carts.

  9. Amine oxidase (copper-containing) - Wikipedia

    en.wikipedia.org/wiki/Amine_oxidase_(copper...

    Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes which includes both primary-amine oxidase and diamine oxidase; these enzymes catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines.