Search results
Results from the WOW.Com Content Network
Alpha 2 blockers. Alpha 2 blockers inhibit the activation of adenylyl cyclase via Gi protein by antagonising alpha 2 receptors, which curbs the synthesis of cyclic AMP (cAMP). [1] This subsequently reduces the concentration of calcium and the release of neurotransmitters, resulting in smooth muscle dilation. [1] Beta 1 blockers
Alpha blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). [2] Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system.
Alpha 1 blocker exerts its action on alpha-1 receptor, dilating the smooth muscles. [3] Alpha-1 receptor is a Gq type G-protein coupled receptor . [ 3 ] When it is activated, it will lead to activation of phospholipase C , raising the intracellular level of IP3 and DAG . [ 3 ]
Isolated vitamin E deficiency or 'ataxia with isolated with vitamin E deficiency' is an inheritable deficiency of vitamin E caused by mutations in the gene for the tocopherol (vitamin E) transfer protein. These patients are the only ones who are unlikely to have other nutrient deficiencies.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Pages for logged out editors learn more
α-Tocopherol (alpha-tocopherol) is a type of vitamin E.Its E number is "E307". Vitamin E exists in eight different forms, four tocopherols and four tocotrienols.All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain, along with an aromatic ring is situated near the carbonyls in the fatty acyl chains of the ...
It has a slower onset and a longer-lasting effect compared with other alpha blockers. It was also the first alpha blocker to be used for treatment of benign prostatic hyperplasia, [2] although it is currently seldom used for that indication due to unfavourable side effects. It has been used in the treatment of hypoplastic left heart syndrome. [3]
Vitamin E was named "tocopherol" (from the Greek words tokos, meaning childbirth, and phero, meaning to bring forth) due to its presumed role in aiding conception. Subsequent research identified eight molecules in the vitamin E family, divided into tocopherols and tocotrienols: alpha, beta, delta, and gamma forms. [ 18 ]