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Schematic drawing of a lung-on-a-chip. The membrane in the middle can be stretched by vacuum in the two side chambers. Lung-on-a-chip (LoC), also known as Lung Chips, are micro- and millifluidic organ-on-a-chip devices designed to replicate the structure and function of the human lung, mimicking the breathing motions and fluid dynamics that occur during inhalation and exhalation. [1]
The jacket ventilator, also known as a poncho or raincoat ventilator, is a lighter version of the iron lung or the cuirass ventilator, constructed of an airtight material (such as plastic or rubber) arranged over a light metal or plastic frame, or screen, and depressurized and repressurized by a portable ventilator. [1] [2] [12] [17]
Liquid ventilator can perform therapeutic lung lavage, the washout of endogenous and exogenous debris from the lungs, without suspension of ventilation support (without apnea). For example, literature data suggest a radical change in the treatment of meconium aspiration syndrome (MAS) by considering the use of a liquid ventilator.
Although total liquid ventilation (TLV) with completely liquid-filled lungs can be beneficial, [9] the complex liquid-filled tube system required is a disadvantage compared to gas ventilation—the system must incorporate a membrane oxygenator, heater, and pumps to deliver to, and remove from the lungs tidal volume aliquots of conditioned perfluorocarbon (PFC).
"A Type A supplied-air respirator equipped with additional devices designed to protect the wearer's head and neck against impact and abrasion from rebounding abrasive material, and with shielding material such as plastic, glass, woven wire, sheet metal, or other suitable material to protect the window(s) of facepieces, hoods, and helmets which ...
The history of mechanical ventilation begins with various versions of what was eventually called the iron lung, a form of noninvasive negative-pressure ventilator widely used during the polio epidemics of the twentieth century after the introduction of the "Drinker respirator" in 1928, improvements introduced by John Haven Emerson in 1931, [5 ...
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The unit administers a set volume (bolus) of oxygen enriched air at the start of each breath, which is the part of the breath most likely to reach the gas exchange regions of the lung beyond the physiological dead space. Their ability to make efficient use of oxygen is key to keeping the units compact. [18]
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