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Prurigo nodularis is hard to treat and therapies include steroids, dupilumab, vitamins, cryosurgery, thalidomide, and UVB light [citation needed]. In the event that staphylococcus or other infection is present, antibiotics have proven effective, but tend to cause more harm than good for this particular disease.
The efficacy and safety of dupilumab to treat prurigo nodularis among adults were evaluated in two clinical trials, EFC16459 (PRIME) and EFC16460 (PRIME2). [10] Each trial evaluated 300 mg of dupilumab administered every 2 weeks following an initial dose of 600 mg. [ 10 ] The treatment lasted for 24 weeks. [ 10 ]
Nemolizumab is indicated for the treatment of adults with prurigo nodularis. [1] [4] In December 2024, the indication for nemolizumab was updated to include the treatment of people twelve years of age and older with moderate-to-severe atopic dermatitis in combination with topical corticosteroids and/or calcineurin inhibitors when the disease is not adequately controlled with topical ...
The FDA grants priority review to Sanofi's (SNY) sBLA for Dupixent to include adults with prurigo nodularis, a chronic inflammatory skin disease.
Lupus erythematosus–lichen planus overlap syndrome (lichen planus–lupus erythematosus overlap syndrome) Methotrexate-induced papular eruption Mixed connective tissue disease (Sharp's syndrome, undifferentiated connective tissue disease)
Prurigo is a reactive skin condition distinguished by numerous, isolated itchy papules. [1] The word "prurigo" comes from the Latin word pruire, which meaning itching. Ferdinand von Hebra coined the term "prurigo" in Vienna in 1850 to describe papules and nodules that had severe pruritus . [ 2 ]
Uremic pruritus is defined as itching that is directly caused by chronic kidney disease, with no other explainable conditions. [14] Uremic pruritus cannot be diagnosed with laboratory tests or established criteria because of its variability and lack of specific skin lesions.
Lupus is a chronic disease that can cause inflammation and pain in any part of the body. The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than ...
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