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Lamotrigine can induce a type of seizure known as a myoclonic jerk, which tends to happen soon after the use of the medication. [69] When used in the treatment of myoclonic epilepsies such as juvenile myoclonic epilepsy, lower doses (and lower plasma levels) are usually needed, as even moderate doses of this drug can induce seizures, including ...
Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [9] It has also been used in alcohol dependence and essential tremor. [9] For epilepsy this includes treatment for generalized or focal seizures. [10] It is taken orally (by mouth). [9]
The first anticonvulsant was bromide, suggested in 1857 by the British gynecologist Charles Locock who used it to treat women with "hysterical epilepsy" (probably catamenial epilepsy). Bromides are effective against epilepsy, and also cause impotence, which is not related to its anti-epileptic effects. Bromide also suffered from the way it ...
The increased need for drugs to treat PTE led to trials with antiepileptics; these early trials suggested that the drugs could prevent epileptogenesis (the development of epilepsy). [19] It was still thought that antiepileptic drugs could prevent epileptogeneis in the 1970s; [ 27 ] in 1973, 60% of physicians surveyed used them to prevent PTE ...
Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset, myoclonic, or tonic–clonic seizures, [7] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein.
The prevalence of seizure clusters is uncertain given that studies have used different definitions to define them. [41] However, estimates suggest that the prevalence may range from 5% to 50% of people with epilepsy. [42] People with refractory epilepsy who have a high seizure frequency are at the greatest risk for having seizure clusters.
“The event or death may have been related to the underlying disease being treated, may have been caused by some other product being used at the same time, or may have occurred for other reasons.” The Times story also cited a buprenorphine study by researchers in Sweden that looked at “100 autopsies where buprenorphine had been detected.”
The risk of sudden death in young adults with epilepsy is increased 20-40-fold compared to the general population. [32] [33] [20] SUDEP is the number one cause of epilepsy-related death in people with pharmacoresistant epilepsy. [20] Children with epilepsy have a cumulative risk of dying suddenly of 7% within 40 years. [20]