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Polysplenia is a congenital disease manifested by multiple small accessory spleens, [1] rather than a single, full-sized, normal spleen.Polysplenia sometimes occurs alone, but it is often accompanied by other developmental abnormalities.
In fact, an enlarged spleen should lead to a search for other possible causes for the thrombocytopenia. Bleeding time is usually prolonged in ITP patients. However, the use of bleeding time in diagnosis is discouraged by the American Society of Hematology practice guidelines [ 15 ] and a normal bleeding time does not exclude a platelet disorder.
However, the understanding of urticaria as an autoimmune condition is a relatively recent development in medical history. [14] The term autoimmune urticaria refers to a subset of chronic spontaneous urticaria (CSU) cases where the immune system appears to play a significant role. This understanding began to evolve in the mid to late 20th ...
The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
Urticaria are characterized by dermal edema (wheal, swollen) and erythema (flare, red), [2] also known as hives. [5] Hive lesions typically last less than 24 hours and are usually itchy (pruritic). [2] Hives can appear anywhere on the body and they may change shape, move around, disappear and reappear over short periods of time. [5]
Hives, also known as urticaria, is a kind of skin rash with red and/or flesh-colored, raised, itchy bumps. [1] Hives may burn or sting. [ 2 ] The patches of rash may appear on different body parts, [ 2 ] with variable duration from minutes to days, and do not leave any long-lasting skin change. [ 2 ]
Hereditary lymphedema is a primary lymphedema – swelling that results from abnormalities in the lymphatic system that are present from birth. Swelling may be present in a single limb, several limbs, genitalia, or the face. It is sometimes diagnosed prenatally by a nuchal scan or postnatally by lymphoscintigraphy. [medical citation needed]
Skin allergies frequently cause rashes, or swelling and inflammation within the skin, in what is known as a "weal and flare" reaction characteristic of hives and angioedema. [30] With insect stings, a large local reaction may occur in the form of an area of skin redness greater than 10 cm in size that can last one to two days. [31]