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Top-p sampling, also called nucleus sampling, is a technique for autoregressive language model decoding proposed by Ari Holtzman in 2019. [1]Before the introduction of nucleus sampling, maximum likelihood decoding and beam search were the standard techniques for text generation, but, both of these decoding strategies are prone to generating texts that are repetitive and otherwise unnatural.
COmet Rendezvous, Sample Acquisition, Investigation, and Return (CORSAIR) is a concept mission to return comet nucleus samples to Earth for detailed analysis.The mission concept was submitted in May 2017 by a team from NASA's Goddard Space Flight Center in response to the New Frontiers program call for mission 4, but did not pass the initial down selection.
A cDNA library is a combination of cloned cDNA (complementary DNA) fragments inserted into a collection of host cells, which constitute some portion of the transcriptome of the organism and are stored as a "library". cDNA is produced from fully transcribed mRNA found in the nucleus and therefore contains only the expressed genes of an organism.
snRNA-seq, also known as single nucleus RNA sequencing, single nuclei RNA sequencing or sNuc-seq, is an RNA sequencing method for profiling gene expression in cells which are difficult to isolate, such as those from tissues that are archived or which are hard to be dissociated.
To obtain a high complexity library of ligation products that will ensure high resolution and depth of data, a sample of 20–25 million cells is required as input for Hi-C. [3] [4] Primary human samples, which may be available only in fewer cell numbers, could be used for standard Hi-C library preparation with as low as 1–5 million cells. [4]
The ESA project was the follow-on Comet Nucleus Sample Return (CNSR) mission. [42] Both missions were to share the Mariner Mark II spacecraft design, thus minimising costs. In 1992, after NASA cancelled CRAF due to budgetary limitations, ESA decided to develop a CRAF-style project on its own. [43]
CITE-Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) is a method for performing RNA sequencing along with gaining quantitative and qualitative information on surface proteins with available antibodies on a single cell level. [1]
YoctoReactor library size. yR library size is a function of the number of different functionalized oligos used in each position and the number of positions in the DNA junction. The yR design approach provides an unvarying reaction site with regard to both (a) distance between reactants and (b) sequence environment surrounding the reaction site.