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  2. Hormone receptor positive breast tumor - Wikipedia

    en.wikipedia.org/wiki/Hormone_receptor_positive...

    ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes [1] that have different prognoses [2] and may have ...

  3. Endocrine therapy resistance in breast cancer - Wikipedia

    en.wikipedia.org/wiki/Endocrine_therapy...

    All of the forms of estrogen found in the human body are able to bind to estrogen receptors (ER) present on cells. This initiates transcription in these cells, resulting in control of gene expression. [12] Treatment strategies that work by blocking the effect of estrogen on breast cancer are referred to as endocrine (or hormone) therapies.

  4. Estrogen receptor - Wikipedia

    en.wikipedia.org/wiki/Estrogen_receptor

    Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry. Two hypotheses have been proposed to explain why this causes tumorigenesis , and the available evidence suggests that both mechanisms contribute:

  5. Breast cancer classification - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_classification

    These treatments are now some of the most effective adjuvant treatments of breast cancer. Estrogen receptor positive (ER+) cancer cells depend on estrogen for their growth, so they can be treated with drugs to reduce either the effect of estrogen (e.g. tamoxifen) or the actual level of estrogen (e.g. aromatase inhibitors), and generally have a ...

  6. Elle Macpherson reveals breast cancer diagnosis, why she ...

    www.aol.com/news/elle-macpherson-reveals-breast...

    Elle Macpherson says she had breast cancer, a diagnosis she kept secret for seven years. The supermodel rejected chemotherapy and choose holistic treatment.

  7. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...

  8. 'Baywatch' star Nicole Eggert missed warning signs of breast ...

    www.aol.com/news/baywatch-star-nicole-eggert...

    According to the Cleveland Clinic, most cribriform carcinoma breast cancer cases are estrogen receptor-positive, occurring when "high levels of estrogen in breast cancer cells help cancer grow and ...

  9. Cancer rates in millennials, Gen X-ers have risen starkly in ...

    www.aol.com/lifestyle/cancer-rates-millennials...

    On average, the rates of 17 types of cancer, including pancreatic, breast and gastric cancer, have risen with each new generation since 1920, the study found. ... Estrogen receptor-positive breast ...

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