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  2. Procaine - Wikipedia

    en.wikipedia.org/wiki/Procaine

    Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain or Novocaine, in some regions, procaine is referred to generically as ...

  3. Procaine benzylpenicillin - Wikipedia

    en.wikipedia.org/wiki/Procaine_benzylpenicillin

    Procaine acts as a local anaesthetic to reduce the discomfort of the depot, while benzylpenicillin enters into circulation and binds to bacterial cell walls, inhibiting their upkeep and production. This eventually leads to cell lysis (bursting). The term "hydrolyzed" is incorrectly used in some medical literature to describe the dissociation of ...

  4. Local anesthetic - Wikipedia

    en.wikipedia.org/wiki/Local_anesthetic

    Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...

  5. Pseudocholinesterase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pseudocholinesterase...

    The effects are varied depending on the particular drug given. When anesthetists administer standard doses of these anesthetic drugs to a person with pseudocholinesterase deficiency, the patient experiences prolonged paralysis of the respiratory muscles, requiring an extended period of time during which the patient must be mechanically ventilated.

  6. Demethylating agent - Wikipedia

    en.wikipedia.org/wiki/Demethylating_agent

    Demethylating agents and their relevance in clinical studies as therapy to treat lymphocytic leukemia can be seen in. [6] Procaine can also be used as therapeutic development to inhibit the growth of cancer cells in humans. There is a new world of possibilities of using demethylating agents to treat different diseases such as leukemia and ...

  7. Theories of general anaesthetic action - Wikipedia

    en.wikipedia.org/wiki/Theories_of_general...

    The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.

  8. General anaesthetic - Wikipedia

    en.wikipedia.org/wiki/General_anaesthetic

    General anaesthetics (or anesthetics) are often defined as compounds that induce a loss of consciousness in humans or loss of righting reflex in animals. Clinical definitions are also extended to include an induced coma that causes lack of awareness to painful stimuli, sufficient to facilitate surgical applications in clinical and veterinary practice.

  9. Endogenous anesthetic - Wikipedia

    en.wikipedia.org/wiki/Endogenous_anesthetic

    Carbon dioxide (CO 2) is an abundant gas produced as the final product of glucose metabolism in animals.CO 2 anesthesia is most frequently used for anesthetizing flies. [2] But it has also been considered as a fast acting anesthetic in small laboratory animals.