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  2. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    In many countries, cocaine is a popular recreational drug. Cocaine use is prevalent across all socioeconomic strata, including age, demographics, economic, social, political, religious, and livelihood. [195] In the United States, the development of "crack" cocaine introduced the substance to a generally poorer inner-city market.

  3. Tusi (drug) - Wikipedia

    en.wikipedia.org/wiki/Tusi_(drug)

    Tusi (also written as tussi, tuci, or tucibi) is a recreational drug that contains a mixture of different psychoactive substances, most commonly found in a pink-dyed powder known as pink cocaine. [ 1 ] [ 2 ] [ 3 ] It is believed to have originated in Latin America around 2018. [ 4 ]

  4. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    In discussing cocaine and related compounds such as amphetamines, it is clear that these psychostimulants cause increased blood pressure, decreased appetite (and hence weight loss), increased locomotor activity (LMA) etc. In the United States, cocaine overdose is one of the leading causes of ER admissions each year due to drug overdose. [175]

  5. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Stimulants or "uppers", such as amphetamines or cocaine, which increase mental or physical function, have an opposite effect to depressants. Depressants, in particular alcohol, can precipitate psychosis .

  6. Speedball (drug) - Wikipedia

    en.wikipedia.org/wiki/Speedball_(drug)

    Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.

  7. As overdose rates rise, FDA calls for new medications to help ...

    www.aol.com/news/why-no-treatments-cocaine-meth...

    The hope is that it will trigger a rush of clinical trial testing for drug treatments for stimulant use disorder, aiming to fill a major gap in the response to the overdose crisis in the U.S ...

  8. Stimulant - Wikipedia

    en.wikipedia.org/wiki/Stimulant

    Cocaine is a stimulant but is not normally prescribed therapeutically for its stimulant properties, although it sees clinical use as a local anesthetic, in particular in ophthalmology. [152] Most cocaine use is recreational and its abuse potential is high (higher than amphetamine), and so its sale and possession are strictly controlled in most ...

  9. List of cocaine analogues - Wikipedia

    en.wikipedia.org/wiki/List_of_cocaine_analogues

    Despite having non-stimulant behavior profiles, they still seem to have anti-depressant behavioral profiles. [ 12 ] The C1 phenyl analog is ten times stronger than cocaine as a dopamine reuptake pump ligand, and twenty four times stronger as a local anesthetic (voltage-dependent Na+ channel blocker), whereas the C1 methyl analog is 2.3 times ...