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Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. [5] [6] [7] Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.
The term cytokeratin began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. [2] In 2006 a new systematic nomenclature for mammalian keratins was created, and the proteins previously called cytokeratins are simply called keratins (human ...
Krukenberg tumors often come to the attention when they cause abdominal or pelvic pain, bloating, ascites, or pain during sexual intercourse.Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in vaginal bleeding, a change in menstrual habits, or hirsutism, [3] or occasionally virilization [4] as a main symptom.
- The right panel shows high magnification on a positive area, confirming adenocarcinoma, as it shows tumor cells with large nuclei and prominent nucleoli. AE1/AE3 is an antibody cocktail that is used in immunohistochemistry , being generally positive in the cytoplasm of carcinomas (cancers of epithelial origin).
general medicine, surgery: varicose veins: superficial vein is percussed proximally; if impulse is felt over vein distally, valvular incompetence is present Budin's sign: Pierre-Constant Budin: surgery, obstetrics: suppurative mastitis: if breast milk flown into a sterile pad is mixed with pus (brown, yellow or bloody traces), mastitis may be ...
The use of ultrasonography in a medical application was first used in the late 1940s in the United States. This use was soon followed in other countries with further research and development being carried out. The first report on Doppler ultrasound as a diagnostic tool for vascular disease was published in 1967–1968.
President-elect Donald Trump complained on Friday that American flags would still be lowered to half-staff in honor of the late President Jimmy Carter during Trump's Jan. 20 inauguration.
For example, a possible outcome of the test would be negative-positive meaning that the initial phase of the test was negative indicating competence in the deep and communicating veins and the second phase of the test was positive meaning that there is superficial vein incompetence. [citation needed]