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Loop diuretics are pharmacological agents that primarily inhibit the Na-K-Cl cotransporter located on the luminal membrane of cells along the thick ascending limb of the loop of Henle. [4] They are often used for the treatment of hypertension and edema secondary to congestive heart failure , liver cirrhosis , or chronic kidney disease .
The term "thiazide" is also often used for drugs with a similar action that do not have the thiazide chemical structure, such as chlorthalidone, metolazone and indapamide. These agents are more properly termed thiazide-like diuretics. [citation needed] Thiazide diuretics also increase calcium reabsorption at the distal tubule.
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Calcium supplements may be a bonus for bone health. But if you’re taking these medications, your supplement might backfire. 5 Ways Your Calcium Supplement May Interact with Medications ...
Mahalini was born into an ethnic Balinese and Hindu family, then she converted to Islam before marrying Rizky Febian. [6] Mahalini started participating in local singing competitions during junior high school. She then continued her education in SMA Negeri 1 Denpasar, where she received an achievement scholarship for her singing ability. [7]
President-elect Donald Trump speaks to members of the media following a meeting at the US Capitol on Jan. 8, 2025 in Washington, DC. Credit - Valerie Plesch—Bloomberg via Getty Images
The U.S Capitol is seen after U.S, President-elect Donald Trump called on U.S. lawmakers to reject a stopgap bill to keep the government funded past Friday, raising the likelihood of a partial ...
Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.