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Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]
Hyperuricaemia or hyperuricemia is an abnormally high level of uric acid in the blood.In the pH conditions of body fluid, uric acid exists largely as urate, the ion form. [1] [2] Serum uric acid concentrations greater than 6 mg/dL for females, 7 mg/dL for males, and 5.5 mg/dL for youth (under 18 years old) are defined as hyperuricemia. [3]
3. Sleep Deprivation. There is a link between sleep loss and weight gain. Research shows that people who routinely don’t get enough sleep tend to eat higher-calorie and higher-fat diets.. Not ...
An evolutionary loss of urate oxidase (uricase), which breaks down uric acid, in humans and higher primates has made this condition common. [5] The triggers for precipitation of uric acid are not well understood. While it may crystallize at normal levels, it is more likely to do so as levels increase.
Here are the best weight loss diets for 2024: WeightWatchers. Mediterranean. Volumetrics. Mayo Clinic Diet. DASH. Flexitarian. Noom Weight. Vegan. Keto. Atkins. These are the best overall diets ...
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine.Protein toxicity has many causes, including urea cycle disorders, genetic mutations, excessive protein intake, and insufficient kidney function, such as chronic kidney disease and acute kidney injury.
While most people typically carry about 10% to 15% visceral fat, having more than that can significantly increase the risk of chronic health conditions like heart disease, diabetes and even cancer.
The legitimate Mayo Clinic Diet does not promote a high protein or "key food" approach. There have been diets falsely attributed to Mayo Clinic for decades. [3] Many or most web sites claiming to debunk the bogus version of the diet are actually promoting it or a similar fad diet.
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