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In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues [1] to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. [2]
Good biomarkers should exhibit good sensitivity (the fraction of correctly identified true positives) and good specificity (the fraction of correctly identified true negatives). A perfect biomarker or biomarker panel would be 100% sensitive (predict all people in the sick group as being sick) and 100% specific (not predicting anyone from the ...
Prognostic markers are biomarkers used to measure the progress of a disease in the patient sample. [1] Prognostic markers are useful to stratify the patients into groups, guiding towards precise medicine discovery. The widely used prognostic markers in cancers include stage, size, grade, node and metastasis. In addition to these common markers ...
An imaging biomarker is a biologic feature, or biomarker detectable in an image. [1] In medicine, an imaging biomarker is a feature of an image relevant to a patient's diagnosis. For example, a number of biomarkers are frequently used to determine risk of lung cancer .
A new approach to a routine blood test could predict a person’s 30-year risk of heart disease, research published Saturday in the New England Journal of Medicine found.. Doctors have long ...
Cardiac markers are biomarkers measured to evaluate heart function. They can be useful in the early prediction or diagnosis of disease. [1] Although they are often discussed in the context of myocardial infarction, other conditions can lead to an elevation in cardiac marker level.
A new study has found that VO2 max is a better measure of cardiovascular health than body mass index (BMI). Here's what it is, plus how it's measured.
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