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Weight gain. Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. ... SNRIs are another class of modern antidepressants. Common SNRIs ...
Many antidepressants, including numerous selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are associated with weight gain.
Through their research, which included 183,118 participants, the study authors found that people taking bupropion (brand name Wellbutrin) were the least likely to experience weight gain, while ...
To date, a great number of potent and selective and mixed norepinephrine reuptake inhibitors (NRIs) have been marketed as antidepressants. [11] The first commercially available selective norepinephrine reuptake inhibitor (sNRI) was reboxetine (Edronax) and was developed as a first-line therapy for major depressive disorder. [29]
This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs, but may be less with atypical antidepressants like bupropion, agomelatine, and vortioxetine. [ 83 ] [ 85 ] [ 86 ] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [ 83 ]
Unlike other antidepressants, bupropion is known to cause fewer and less severe adverse symptoms, like drowsiness, weight loss, weight gain and intimate dysfunction.
For example, cocaine, which non-selectively inhibits the reuptake of serotonin, norepinephrine, and dopamine, is an SRI but not an SSRI. SRIs are used predominantly as antidepressants (e.g., SSRIs, SNRIs, and TCAs), though they are also commonly used in the treatment of other psychological conditions such as anxiety disorders and eating disorders.
Weight gain can be a side effect of antidepressants for some people. Here is how much weight you might gain on each of eight common antidepressants. Some antidepressants contribute to weight gain ...