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Diabetes in the mother during pregnancy is a significant risk factor for autism; a 2009 meta-analysis found that gestational diabetes was associated with a twofold increased risk. A 2014 review also found that maternal diabetes was significantly associated with an increased risk of autism. [ 55 ]
[11] [12] [13] Maternal valproate use during pregnancy increased the probability of autism in the offspring compared to mothers not taking valproate from 1.5% to 4.4%. [14] A 2005 study found rates of autism among children exposed to sodium valproate before birth in the cohort studied were 8.9%. [15]
Several prenatal and perinatal complications have been reported as possible risk factors for autism. These risk factors include maternal gestational diabetes, maternal and paternal age over 30, [198] [199] [200] bleeding during pregnancy after the first trimester, use of certain prescription medication (e.g. valproate) during pregnancy, and ...
The risk of developing autism is increased in the presence of various prenatal factors, including advanced paternal age and diabetes in the mother during pregnancy. [8] In rare cases, autism is strongly associated with agents that cause birth defects. [9] It has been shown to be related to genetic disorders [10] and with epilepsy. [11]
Omega-3 supplements during pregnancy were not associated with autism diagnosis or autism-related traits, the researchers said. Autism is a developmental condition that affects how people learn ...
A few genetic polymorphisms such as folate hydrolase 1 and hydroxymethyltransferase 1 along with hyperhomocysteinemia were used as risk factors to develop an artificial neural network (ANN). Studies showed that this model was around 63.8% accurate in predicting ASD risk, implying a moderate association between genetic polymorphisms of the ...
After adjusting for factors such as mother’s age, smoking status and maternal diagnoses of autism, ADHD and intellectual disability, the researchers found that among those children whose mothers ...
Autism concordance in siblings and fraternal twins is anywhere between 0 and 23.5%. This is more likely 2–4% for classic autism and 10–20% for a broader spectrum. Assuming a general-population prevalence of 0.1%, the risk of classic autism in siblings is 20- to 40-fold that of the general population.