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  2. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Improper chromosome segregation (see non-disjunction, disomy) can result in aneuploid gametes having either too few or too many chromosomes. The second stage at which segregation occurs during meiosis is prophase II (see meiosis diagram). During this stage, segregation occurs by a process similar to that during mitosis, except that in this case ...

  3. Meiosis - Wikipedia

    en.wikipedia.org/wiki/Meiosis

    Meiosis II is the second meiotic division, and usually involves equational segregation, or separation of sister chromatids. Mechanically, the process is similar to mitosis, though its genetic results are fundamentally different.

  4. Zygotene - Wikipedia

    en.wikipedia.org/wiki/Zygotene

    The zygotene stage is crucial for genetic recombination and proper chromosome segregation in meiosis. [1] Defects in synapsis, recombination, or crossover regulation can lead to aneuploidy and chromosomal abnormalities in gametes. [11]

  5. Chromosomal crossover - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_crossover

    Crossing over is important for the normal segregation of chromosomes during meiosis. [2] Crossing over also accounts for genetic variation, because due to the swapping of genetic material during crossing over, the chromatids held together by the centromere are no longer identical.

  6. Non-random segregation of chromosomes - Wikipedia

    en.wikipedia.org/wiki/Non-random_segregation_of...

    Non-random segregation of chromosomes is a deviation from the usual distribution of chromosomes during meiosis, that is, during segregation of the genome among gametes.While usually according to the 2nd Mendelian rule (“Law of Segregation of genes“) homologous chromosomes are randomly distributed among daughter nuclei, there are various modes deviating from this in numerous organisms that ...

  7. Origin and function of meiosis - Wikipedia

    en.wikipedia.org/wiki/Origin_and_function_of_meiosis

    Meiosis generates genetic variation in the diploid cell, in part by the exchange of genetic information between the pairs of chromosomes after they align (recombination). Thus, on this view, [28] an advantage of meiosis is that it facilitates the generation of genomic diversity among progeny, allowing adaptation to adverse changes in the ...

  8. Meiotic drive - Wikipedia

    en.wikipedia.org/wiki/Meiotic_drive

    According to Buckler et al., "Meiotic drive is the subversion of meiosis so that particular genes are preferentially transmitted to the progeny. Meiotic drive generally causes the preferential segregation of small regions of the genome". [1]

  9. Genetic linkage - Wikipedia

    en.wikipedia.org/wiki/Genetic_linkage

    During meiosis, chromosomes assort randomly into gametes, such that the segregation of alleles of one gene is independent of alleles of another gene. This is stated in Mendel's Second Law and is known as the law of independent assortment. The law of independent assortment always holds true for genes that are located on different chromosomes ...