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Polyene antimycotics, sometimes referred to as polyene antibiotics, are a class of antimicrobial polyene compounds that target fungi. [1] These polyene antimycotics are typically obtained from certain species of Streptomyces bacteria. Previously, polyenes were thought to bind to ergosterol in the fungal cell membrane, weakening it and causing ...
Appearance. A mycotoxin (from the Greek μύκης mykes, "fungus" and τοξικός toxikos, "poisonous") [ 1 ][ 2 ] is a toxic secondary metabolite produced by fungi [ 3 ][ 4 ] and is capable of causing disease and death in both humans and other animals. [ 5 ][ 6 ] The term 'mycotoxin' is usually reserved for the toxic chemical products ...
Medicinal uses of fungi. Appearance. Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs. Compounds successfully developed into drugs or under research include antibiotics, anti-cancer drugs, cholesterol and ergosterol synthesis inhibitors, psychotropic ...
Fungal infection, also known as mycosis, is a disease caused by fungi. [5][13] Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous, and systemic. [3][6] Superficial fungal infections include common tinea of the skin, such as tinea of the body, groin, hands, feet and beard, and yeast ...
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
Contents. Discovery and development of cephalosporins. Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with other β-lactam antibiotics (e.g. penicillins, carbapenems and monobactams). [ 1 ] The cephalosporins (and other β-lactams) have the ...
Microbial toxins are toxins produced by micro-organisms, including bacteria, fungi, protozoa, dinoflagellates, and viruses. Many microbial toxins promote infection and disease by directly damaging host tissues and by disabling the immune system. Endotoxins most commonly refer to the lipopolysaccharide (LPS) or lipooligosaccharide (LOS) that are ...
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. [1][2] They may either kill or inhibit the growth of bacteria.