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[1] [2] The diagnosis is challenging, primarily because symptoms often mimic more common and benign degenerative spinal diseases. [8] [9] Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a ...
Patient response to treatment will vary based on age, health, and the tolerance to medications and therapies. Metastasis occurs in about 39% of patients, most commonly to the lung. Features associated with poor prognosis include a large primary tumor (over 5 cm across), high grade disease, co-existent neurofibromatosis, and the presence of ...
Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones. Bone-originating primary tumors such as osteosarcoma , chondrosarcoma , and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [ 1 ]
Metastasis occurrence indicates stage 4 cancer progression and carries a poor prognosis. [7] Cancer usually causes numerous and varying symptoms at this stage depending on the underlying cancer and metastasis location. [7] Importantly for diagnosis, a symptomatic primary lesion is localised through either surgery or radiation. [7]
Symptoms suggestive of cord compression are back pain, a dermatome of increased sensation, paralysis of limbs below the level of compression, decreased sensation below the level of compression, urinary and fecal incontinence and/or urinary retention. Lhermitte's sign (intermittent shooting electrical sensation) and hyperreflexia may be present.
With increasing cancer treatment survival rates, the quality of life for its survivors has become a public health priority. [1] The effects of RILP can be debilitating. With no effective treatment to control radiation damage's progressive nature, limb dysfunction is the likely result. [10] Radiation damage's outcome is related to its initial ...
Once a cancer has metastasized, prognosis normally becomes much worse. About half of patients receiving treatment for invasive cancer (excluding carcinoma in situ and non-melanoma skin cancers) die from that cancer or its treatment. [24] A majority of cancer deaths are due to metastases of the primary tumor. [202]
The surgeries and complex treatment regimens used in cancer therapy have led the term to be used mainly to describe adjuvant cancer treatments. An example of such adjuvant therapy is the additional treatment [ 1 ] usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due ...
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