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Post-nasal drip (PND), also known as upper airway cough syndrome (UACS), occurs when excessive mucus is produced by the nasal mucosa. The excess mucus accumulates in the back of the nose , and eventually in the throat once it drips down the back of the throat.
Also called rhinorrhea, is a very common medical disorder that occurs when the nasal tissues are congested and the excess fluid runs either at the back of the throat or out of the nose. Post-nasal drip can be caused by the common cold, allergies to dust, smoking, or pet dander. Even spicy foods can sometimes cause post-nasal drip.
Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. [4] The inflammation is caused by viruses, bacteria, irritants or allergens. The most common kind of rhinitis is allergic rhinitis, [5] which is usually triggered by airborne allergens such as pollen and dander. [6]
Postnasal drip coughing can be caused by the direct irritation of the postnasal drip or by inflammation of cough receptors in the upper airway. Postnasal drip cases contribute 34% of chronic cough cases. [17] Asthma that affects the upper respiratory tract. Other causes such as cold air or breathing in chemicals can also induce coughing. [18]
Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold, irritable bowel syndrome and allergy medications [2] Methscopolamine, a methylated derivative of scopolamine, is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine.
Irregular coughing is usually caused by a respiratory tract infection but can also be triggered by choking, smoking, air pollution, [1] asthma, gastroesophageal reflux disease, post-nasal drip, chronic bronchitis, lung tumors, heart failure and medications such as angiotensin-converting-enzyme inhibitors (ACE inhibitors) and beta blockers. [2]
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