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7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [ 1 ] [ 2 ] Pharmacodynamics
In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56] As DHEA-S can be converted back into DHEA, it serves as a circulating reservoir for DHEA, thereby extending the duration of DHEA. [57] [20] Metabolites of DHEA include DHEA-S, 7α-hydroxy-DHEA, 7β-hydroxy-DHEA, 7-keto-DHEA, 7α-hydroxyepiandrosterone, and 7β ...
Over-the-counter DHEA supplements are also available for men and women. DHEA is said to be good for: ED. Depression. Aging skin. Infertility. Muscle strength. Heart disease.
All those preoccupied with weight control should consider supplementation in 7-Keto DHEA. • All those taking DHEA can take 7-Keto DHEA if they are willing to pay a little more for a more effective and safer supplement. Those who cannot take DHEA because of the risk of hormonal-dependent cancer can take 7-Keto DHEA.
7 Supplement Combos You Should Never Take Together, According to Dietitians. Isabel Vasquez, RD, LDN. January 8, 2025 at 8:57 PM. Reviewed by Dietitian Maria Laura Haddad-Garcia.
[1] [2] It is the 3α-epimer of dehydroepiandrosterone (DHEA; androst-5-en-3β-ol-17-one) and the 5(6)-dehydrogenated and non-5α-reduced analogue of androsterone (5α-androstan-3α-ol-17-one). [2] DHA is produced in and secreted from the adrenal glands , along with other weak androgens like DHEA, androstenediol , and androstenedione .
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