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Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.
Fibrocyte cells normally secrete collagen, and function to provide structural support for the heart. When over-activated this process causes thickening and fibrosis of the valve, with white tissue building up primarily on the tricuspid valve, but also occurring on the pulmonary valve.
Interstitial cell refers to any cell that lies in the spaces between the functional cells of a tissue. Examples include: Interstitial cell of Cajal (ICC) Leydig cells, cells present in the male testes responsible for the production of androgen (male sex hormone) A portion of the stroma of ovary; Certain cells in the pineal gland; Renal ...
Mitral valve prolapse classification. Diagnosis of mitral valve prolapse is based on modern echocardiographic techniques which can pinpoint abnormal leaflet thickening and other related pathology. Echocardiography is the most useful method of diagnosing a prolapsed mitral valve. Two- and three-dimensional echocardiography is particularly ...
[2] [3] Thus, in situ (in its original position or place) tissue engineering of heart valves serves as a novel approach that explores the use creating a living heart valve composed of the host's own cells that is capable of growing, adapting, and interacting within the human body's biological system. [4]
The Summary. A NASA spacecraft brought samples from the asteroid Bennu back to Earth in 2023. The first in-depth analyses of that material have revealed organic molecules, including building ...
A valve system in place here prevents the absorbed lymph from leaking back into the interstital fluid. This valve system involves collagen fibers attached to lymphatic endothelial cells that respond to increased interstitial fluid pressure by separating the endothelial cells and allowing the flow of lymph into the capillary for circulation. [5]
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