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Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...
Database Institute / Organization Alteration Types Primary Source [t 1] Processed Data [t 2] Organisms Cell lines [t 3] Public Data [t 4] Restricted Data [t 5]; The BioExpress® Oncology Suite from Ocimum Bio Solutions contains gene expression data from primary, metastatic, and benign tumor samples, and normal samples, including matched adjacent controls.
Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely. A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line. [7]
This list, containing 488 cell lines, was last updated on 1 December 2016. [c] Cellosaurus also is maintaining a list of "problematic" cell lines. [6] The list is dynamically generated from all cell lines in the database with a comment containing the dedicated words "Problematic cell line". As of 17 January 2017, the list contains 757 entries.
This is an accepted version of this page This is the latest accepted revision, reviewed on 16 February 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
The cell line is a great model for breast cancer cells because the cells proliferate at a fast rate and is stimulated by androgens, but inhibited by progesterone, estrogen, and Her-2 receptors. The specific mutation that contributes to the cell cancer line is a glutamate to histidine change found on exon 7; more specifically, the amino acid 865.
MCF-7 cells. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos Cancer ...
4T1 cell culture - 50% confluence. 4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. [1] 4T1 cells are epithelial and are resistant to 6-thioguanine. [1] In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes ...
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