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In the United states, natalizumab is indicated for the treatment of multiple sclerosis and Crohn's disease. [1] [9] It is indicated to treat clinically isolated syndrome – a single, first occurrence of multiple sclerosis symptoms; relapsing-remitting disease – a type of multiple sclerosis that occurs when people have episodes of new neurological symptoms followed by periods of stability ...
MSYS2 ("minimal system 2") is a software distribution and a development platform for Microsoft Windows, based on Mingw-w64 and Cygwin, that helps to deploy code from the Unix world on Windows. It plays the same role the old MSYS did in MinGW.
Similar to acetic anhydride, trifluoroacetic anhydride can be used as a dehydrating agent and as an activator for the Pummerer rearrangement. [4] It can be used in place of oxalyl chloride in the Swern oxidation, allowing temperatures up to −30 °C. [5] With sodium iodide, it reduces sulfoxides to sulfides. [4]
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Sample preparation for mass spectrometry is used for the optimization of a sample for analysis in a mass spectrometer (MS). Each ionization method has certain factors that must be considered for that method to be successful, such as volume, concentration , sample phase, and composition of the analyte solution.
Computer-assisted organic synthesis software is a type of application software used in organic chemistry in tandem with computational chemistry to help facilitate the tasks of designing, predicting, and producing chemical reactions. CAOS aims to identify a series of chemical reactions which, from a starting compound, can produce a desired molecule.
2-Methoxyethoxymethyl chloride is an organic compound with formula CH 3 OCH 2 CH 2 OCH 2 Cl.A colorless liquid, it is classified as a chloroalkyl ether.It is used as an alkylating agent.
The main objective of developing and evaluating an IVIVC is to establish the dissolution test as a surrogate for human studies, as stated by the Food and Drug Administration (FDA). [5] Analytical data from drug dissolution testing are sufficient in many cases to establish safety and efficacy of a drug product without in vivo tests, following ...
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