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Stannous fluoride is an alternative to sodium fluoride for the prevention of cavities (tooth decay). It was first released commercially in 1956, in Crest toothpaste. It was discovered and developed by Joseph Muhler and William Nebergall. In recognition of their innovation, they were inducted into the Inventor's Hall of Fame. [1]
The types of fluoride added to toothpaste include: sodium fluoride, sodium monofluorophosphate (MFP), and stannous fluoride. [21] [22] As stated previously, fluoride has been proven to positively affect the remineralization process through fluorapatite-like veneer formation.
Fluoride-containing toothpaste can be classified into two types, namely low-fluoride and high-fluoride toothpaste. [12] Low-fluoride toothpaste, depending on brand, generally contains 0.22% to 0.31% fluoride. [12] These fluorides are often manufactured in the form of sodium fluoride, stannous fluoride, or sodium monofluorophosphate (MFP). [4]
Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Fluoride therapy typically uses the sodium fluoride form, though stannous fluoride may also be used. [4] [5] Fluoride decreases breakdown of teeth by acids, promotes remineralisation, and decreases the activity of bacteria. [5] Fluoride works primarily through direct contact with teeth. [3] [5] Fluoride came into use to prevent tooth decay in ...
Researchers concluded that pregnant women may want to avoid fluoride. “We have a possible risk,” an author of the study, Dr. Bruce Lanphear, a professor of health sciences at Simon Fraser ...
A U.S. government report expected to stir debate concluded that fluoride in drinking water at twice the recommended limit is linked with lower IQ in children. The report, based on an analysis of ...
Tin(II) fluoride is added to some dental care products [111] as stannous fluoride (SnF 2). Tin(II) fluoride can be mixed with calcium abrasives while the more common sodium fluoride gradually becomes biologically inactive in the presence of calcium compounds. [112] It has also been shown to be more effective than sodium fluoride in controlling ...