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  2. Guanidinium chloride - Wikipedia

    en.wikipedia.org/wiki/Guanidinium_chloride

    Guanidinium chloride or guanidine hydrochloride, usually abbreviated GdmCl and sometimes GdnHCl or GuHCl, is the hydrochloride salt of guanidine. Structure

  3. Guanidine - Wikipedia

    en.wikipedia.org/wiki/Guanidine

    Guanidine exists protonated, as guanidinium, in solution at physiological pH. Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins. Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfolding.

  4. Guanidinium thiocyanate - Wikipedia

    en.wikipedia.org/wiki/Guanidinium_thiocyanate

    Guanidinium thiocyanate can be used to deactivate a virus, such as the influenza virus that caused the 1918 "Spanish flu", so that it can be studied safely.. Guanidinium thiocyanate is also used to lyse cells and virus particles in RNA and DNA extractions, where its function, in addition to its lysing action, is to prevent activity of RNase enzymes and DNase enzymes by denaturing them.

  5. Polyhexamethylene guanidine - Wikipedia

    en.wikipedia.org/wiki/Polyhexamethylene_guanidine

    Polyhexamethylene guanidine (PHMG) is a guanidine derivative that is used as a biocidal disinfectant, often in the form of its salt polyhexamethylene guanidine phosphate (PHMG-P). Studies have shown that PHMG in solution has fungicidal as well as bactericidal activity against both Gram-positive and Gram-negative bacteria . [ 2 ]

  6. Native chemical ligation - Wikipedia

    en.wikipedia.org/wiki/Native_chemical_ligation

    It involves the reaction of an unprotected peptide thioester with a second, unprotected peptide that has an N-terminal cysteine residue. It is carried out in aqueous solution at neutral pH, usually in 6 M guanidine.hydrochloride, in the presence of an arylthiol catalyst and typically gives near-quantitative yields of the desired ligation product.

  7. Guanfacine - Wikipedia

    en.wikipedia.org/wiki/Guanfacine

    1 mg guanfacine tablets. Guanfacine is FDA-approved as monotherapy or augmentation with stimulants to treat attention deficit hyperactivity disorder (ADHD). [3] [16] [17] Unlike stimulant medications, guanfacine is regarded as having no abuse potential, and may even be used to reduce abuse of drugs including nicotine and cocaine. [18]

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