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The Koenigsegg TFG is an inline-3 engine. The TFG stands for "Tiny Friendly Giant." It is a Freevalve (camless piston engine), thus it does not have a camshaft.Instead it uses electro-hydraulic-pneumatic actuators that allow it to open each valve (both intake and exhaust) independently to maximise performance and minimise fuel consumption depending on driving conditions.
These are upregulated in Marfan's syndrome [1] [2] and some human cancers, and play crucial roles in tissue regeneration, cell differentiation, embryonic development, and regulation of the immune system. [3] [4] Isoforms of transforming growth factor-beta (TGF-β1) are also thought to be involved in the pathogenesis of pre-eclampsia. [5]
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three [1] different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins. TGFB proteins are produced by all white blood cell lineages.