Search results
Results from the WOW.Com Content Network
Since 2009, two tyrosine kinase inhibitors - masitinib (trade name Masivet) and toceranib (trade name Palladia) - have been approved for the treatment of mastocytomas in dogs in the EU. [17] [37] [38] Masitinib is approved for the treatment of unresectable grade 2 and 3 (or high-grade) mastocytomas with c-KIT mutation.
Toceranib and masitinib, examples of receptor tyrosine kinase inhibitors, are used in the treatment [11] [12] of canine mast cell tumors. Both were recently approved by the U.S. Food and Drug Administration (FDA) [13] [14] as dog-specific anticancer drugs. [15] Grade I or II mast cell tumors that can be completely removed have a good prognosis.
There are three main treatment options available to treat soft tissue sarcoma in cats and dogs: surgery, radiation therapy, and chemotherapy. Surgery alone or in combination with radiation therapy are used to treat the tumor at its original location, and chemotherapy is usually used to prevent or at least slow down the process of metastasis in ...
As in dogs, tumor size is an important prognostic factor, although for tumors less than three centimeters the individual size is less predictive. According to one study, cats with tumors less than three cm had an average survival time of 21 months, and cats with tumors greater than three cm had an average survival of 12 months. [ 17 ]
Patients in response categories 4-9 should be considered as failing to respond to treatment (disease progression). Thus, an incorrect treatment schedule or drug administration does not result in exclusion from the analysis of the response rate. Precise definitions for categories 4-9 will be protocol specific.
The soft fibroma (fibroma molle) or fibroma with a shaft (acrochordon, skin tag, fibroma pendulans) consist of many loosely connected cells and less fibroid tissue. [3]It mostly appears at the neck, armpits or groin.
A vaccine-associated sarcoma (VAS) or feline injection-site sarcoma (FISS) is a type of malignant tumor found in cats (and, often, dogs and ferrets) which has been linked to certain vaccines. VAS has become a concern for veterinarians and cat owners alike and has resulted in changes in recommended vaccine protocols.
Current cure rates using stem cell therapy in dogs approximates that achieved in humans, 40-50%. When cost is a factor, prednisone used alone can improve the symptoms dramatically, but it does not significantly affect the survival rate. The average survival times of dogs treated with prednisone and untreated dogs are both one to two months. [1]