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Synapsis during Meiosis. The circled area is the part where synapsis occurs, where the two chromatids meet before crossing over. Synapsis or Syzygy is the pairing of two chromosomes that occurs during meiosis. It allows matching-up of homologous pairs prior to their segregation, and possible chromosomal crossover between them.
The linked frequency of crossing over between two gene loci is the crossing-over value. For fixed set of genetic and environmental conditions, recombination in a particular region of a linkage structure ( chromosome ) tends to be constant and the same is then true for the crossing-over value which is used in the production of genetic maps .
During synapsis, genetic recombination usually occurs. Some of the recombination events occur by crossing over (involving physical exchange between two chromatids), but most recombination events involve information exchange but not physical exchange between two chromatids (see Synthesis-dependent strand annealing (SDSA) ).
The synaptonemal complex (SC) is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought to mediate synapsis and recombination during prophase I during meiosis in eukaryotes.
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
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Points of crossing over become visible as chiasma after the synaptonemal complex dissembles and the homologous chromosomes slightly apart from each other. The phenomenon of genetic chiasmata ( chiasmatypie ) was discovered and described in 1909 by Frans Alfons Janssens , a Professor at the University of Leuven in Belgium .