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1:30,000 (males), 1:125,000 (females) Kallmann syndrome (KS) is a genetic disorder that prevents a person from starting or fully completing puberty. Kallmann syndrome is a form of a group of conditions termed hypogonadotropic hypogonadism. [1] To distinguish it from other forms of hypogonadotropic hypogonadism, Kallmann syndrome has the ...
Age and female fertility. Female fertility is affected by age and is a major fertility factor for women. A woman's fertility is in generally good quality from the late teens to early thirties, although it declines gradually over time. [1] Around 35, fertility is noted to decline at a more rapid rate. [1] At age 45, a woman starting to try to ...
Human genetic variants that likely cause dysregulation of critical meiotic processes have been identified in 14 female infertility associated genes. [53] A major cause of female infertility is premature ovarian insufficiency. [54] This insufficiency is a heterogeneous disease that affects about 1% of women who are under the age of 40. [54]
Most of these patients have multiple pituitary hormone deficiencies. [5] Hyperprolactinaemia is the most common cause of AHH. It is a well-established cause of infertility in both male and female mammals. [6] Prolactin inhibits GnRH neurons and therefore inhibits the subsequent release of LH, FSH and sex steroids.
Primary ovarian insufficiency (POI), also called premature ovarian insufficiency, premature menopause, and premature ovarian failure, is the partial or total loss of reproductive and hormonal function of the ovaries before age 40 because of follicular (egg producing area) dysfunction or early loss of eggs. [ 1 ][ 4 ][ 6 ] POI can be seen as ...
Hyperandrogenism affects 5–10% of women of reproductive age. [11] Hyperandrogenism can affect both men and women but is more noticeable in women since elevated levels of androgens in women may facilitate virilization. Because hyperandrogenism is characterized by elevated male sex hormone levels, symptoms of hyperandrogenism in men are often ...
Androgen deficiency is a medical condition characterized by insufficient androgenic activity in the body. Androgen deficiency most commonly affects women, and is also called Female androgen insufficiency syndrome (FAIS), although it can happen in both sexes. [2][3] Androgenic activity is mediated by androgens (a class of steroid hormones with ...
Common in males: low sperm count, abnormal sperm morphology. Frequency. 113 million (2015) [1] Infertility is the inability of an animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects).