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Metreleptin, sold under the brand name Myalept among others, is a synthetic analog of the hormone leptin used to treat various forms of dyslipidemia.It has been approved in Japan for metabolic disorders including lipodystrophy and in the United States as replacement therapy to treat the complications of leptin deficiency, in addition to diet, in patients with congenital generalized or acquired ...
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Amylin Ohio LLC. Amylin Pharmaceuticals, Inc. is a biopharmaceutical founded in 1987 that was based in San Diego, California. The company was engaged in the discovery, development, and commercialization of drug candidates for the treatment of diabetes, obesity, and other diseases. Amylin produced three drugs: Symlin (pramlintide acetate ...
16846 Ensembl ENSG00000174697 ENSMUSG00000059201 UniProt P41159 P41160 RefSeq (mRNA) NM_000230 NM_008493 RefSeq (protein) NP_000221 NP_032519 Location (UCSC) Chr 7: 128.24 – 128.26 Mb Chr 6: 29.06 – 29.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Leptin Structure of the obese protein leptin-E100 Identifiers Symbol Leptin Pfam PF02024 Pfam clan CL0053 InterPro IPR000065 ...
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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [ 4 ][ 6 ] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant ...