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Clomid does help infertility in some men, though the outcomes can vary in their timeline. The most obvious sign that Clomid for fertility is working is that your partner is expecting a child.
Clomifene citrate (Clomid is a common brand name) is the medication which is most commonly used to treat anovulation. It is a selective estrogen-receptor modulator, affecting the hypothalamic–pituitary–gonadal axis to respond as if there was an estrogen deficit in the body, in effect increasing the production of follicle-stimulating hormone.
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle . In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty , [ 1 ] [ 2 ] each with the potential to release an egg cell (ovum) at ovulation for fertilization ...
The primary role of the follicle is oocyte support. From the whole pool of follicles a woman is born with, only 0.1% of them will rise ovulation, whereas 99.9% will break down (in a process called follicular atresia).
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [ 2 ] and regulates the development, growth, pubertal maturation , and reproductive processes of the body.
Preparations of follicle-stimulating hormone (FSH) mainly include those derived from the urine of menopausal women, as well as recombinant preparations. The recombinant preparations are more pure and more easily administered, but they are more expensive.
Clomifene has been used almost exclusively for ovulation induction in premenopausal women, and has been studied very limitedly in postmenopausal women. [ 64 ] Clomifene was studied for treatment and prevention of breast cancer , but issues with toxicity led to abandonment of this indication, as did the discovery of tamoxifen . [ 65 ]
Low follicle count (1-3): low ovarian reserve and increased risk of menopause in the next 7 years. Normal follicle count (4-24): Normal follicle amount for women in reproductive age. High follicle count (>=): High risk of hyperandrogenism. It has been suggested that counting the antral follicles measuring 2–5 or 4–6 mm in diameter is ...