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Alternative online IC50 calculator (www.ic50.org) based on Python, NumPy, SciPy and Matplotlib; ELISA IC50/EC50 Online Tool (link seems broken) IC50 to pIC50 calculator; Online tool for analysis of in vitro resistance to antimalarial drugs; IC50-to-Ki converter of an inhibitor and enzyme that obey classic Michaelis-Menten kinetics
Lipophilic efficiency [1] (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness.
Ligand efficiency is a measurement of the binding energy per atom of a ligand to its binding partner, such as a receptor or enzyme. [1]Ligand efficiency is used in drug discovery research programs to assist in narrowing focus to lead compounds with optimal combinations of physicochemical properties and pharmacological properties.
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Inhibitors have IC50 values so I tried to reintegrate it with information already present in the article. I think that including it in the lead paragraph would mislead people into thinking it was a discussion about inhibitors not The IC50 concept Lilypink 19:04, 5 November 2007 (UTC) IC50 is not a pharmacological constant! pA2 is a constant.
The following table compares general and technical information for a selection of common and uncommon Texas Instruments graphing calculators. Many of the calculators in this list have region-specific models that are not individually listed here, such as the TI-84 Plus CE-T, a TI-84 Plus CE designed for non-French European markets.
The HP 35s (F2215A) is a Hewlett-Packard non-graphing programmable scientific calculator. Although it is a successor to the HP 33s, it was introduced to commemorate the 35th anniversary of the HP-35, Hewlett-Packard's first pocket calculator (and the world's first pocket scientific calculator).
A difference engine is an automatic mechanical calculator designed to tabulate polynomial functions. It was designed in the 1820s, and was first created by Charles Babbage . The name difference engine is derived from the method of finite differences , a way to interpolate or tabulate functions by using a small set of polynomial co-efficients.