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The notion of doubling time dates to interest on loans in Babylonian mathematics. Clay tablets from circa 2000 BCE include the exercise "Given an interest rate of 1/60 per month (no compounding), come the doubling time." This yields an annual interest rate of 12/60 = 20%, and hence a doubling time of 100% growth/20% growth per year = 5 years.
The doubling time can range from 2.5–4h depending on the media, culture format, and level of aeration. [12] At temperatures above 30 °C (86 °F), A. tumefaciens begins to experience heat shock which is likely to result in errors in cell division. [12]
The LNCaP (Lymph Node Carcinoma of the Prostate) cell line was established from a metastatic lesion of human prostatic adenocarcinoma.The LNCaP cells grow readily in vitro (up to 8 x 10 5 cells/sq cm; doubling time, 60 hr), form clones and are highly resistant to human fibroblast interferon. [1]
Small-cell lung carcinoma (SCLC) has long been divided into two clinicopathological stages, termed limited stage (LS) and extensive stage (ES). [8] The stage is generally determined by the presence or absence of metastases, whether or not the tumor appears limited to the thorax, and whether or not the entire tumor burden within the chest can feasibly be encompassed within a single radiotherapy ...
The panel holds cell lines representing leukemia, melanoma, non-small-cell lung carcinoma, and cancers of the brain, ovary, breast, colon, kidney, and prostate. [1] [2]13 additional cell lines are evaluated for use in the screening program, among them two lines deriving from so far not represented small-cell lung carcinoma.
The doubling time is about 36–48 hours. The cell line was derived from a 36-year-old woman who was originally reported to have acute promyelocytic leukemia at the MD Anderson Cancer Center. [1] HL-60 cells predominantly show neutrophilic promyelocytic morphology. [1]
2). Their average doubling time is 14 hours. Their average doubling time is 14 hours. The base medium for this cell line is RPMI-1640 Medium with a fetal bovine serum in a final concentration of 10%. 4T1 cells should not be allowed to become 100% confluent.
Early on it was found that X-rays, gamma rays, and beta radiation were essentially equivalent for all cell types. Therefore, the standard radiation type X is generally an X-ray beam with 250 keV photons or cobalt-60 gamma rays. As a result, the relative biological effectiveness of beta and photon radiation is essentially 1.