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Wolff's law, developed by the German anatomist and surgeon Julius Wolff (1836–1902) in the 19th century, states that bone in a healthy animal will adapt to the loads under which it is placed. [1] If loading on a particular bone increases, the bone will remodel itself over time to become stronger to resist that sort of loading.
The basis of osteogenic loading stems from Wolff's law, [5] which shows that the force or loading on bone through its axis, can stimulate the bone's natural function of increasing in density. Further study has shown that greater loads on bone can stimulate a greater effect of the body to respond and increase the density of bone, and can show ...
The Mechanostat is often defined as a practical description of Wolff's law described by Julius Wolff (1836–1902), but this is not completely accurate. Wolff wrote his treatises on bone after images of bone sections were described by Culmann and von Meyer, who suggested that the arrangement of the struts (trabeculae) at the ends of the bones ...
This is because by Wolff's law, [2] bone in a healthy person or animal remodels in response to the loads it is placed under. It is possible to mention the elastic modulus of magnesium (41–45 GPa) compared to titanium (110–127 GPa), stainless steel (189–205 GPa), iron (211.4 GPa), or zinc (78–121 GPa), which makes it further analogous to ...
Wolff's Law is indeed the beginning of research into the relation of muscle and bone. The Mechanostat Model, described by Harold Frost in the late 1960's, is a huge extension and refinement of Wolff's law. There have been heaps of studies since the 60s in this field - various animal studies as well as human studies.
Davis's law is used in anatomy and physiology to describe how soft tissue models along imposed demands. It is similar to Wolff's law , which applies to osseous tissue . It is a physiological principle stating that soft tissue heal according to the manner in which they are mechanically stressed.
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
Wolf's Law is the second full-length studio album from Welsh alternative rock band the Joy Formidable. The album was released on 21 January 2013 in the United Kingdom, and on 22 January 2013 in the United States, on Atlantic Records .